Dr. Hannah Lemke
Foto: Hannah Lemke
Postdoc
Kinder- und Jugendlichenpsychotherapie
Anschrift
Büro
Kontakt
Wissenschaftliche und Klinische Tätigkeit
| Seit 04/2025 | Wissenschaftliche Mitarbeiterin (Post Doc), Institut für Psychologie, Arbeitsbereich Kinder- und Jugendlichenpsychotherapie, Universität Hamburg |
| Seit 05/2023 | Wissenschaftliche Mitarbeiterin (Post Doc), Asklepios Klinik Nord-Ochsenzoll, Asklepios Campus Hamburg |
| 10/2023 - 03/2025 | Psychologin, Tagesklinik für Gerontopsychiatrie, Asklepios Klinik Nord-Ochsenzoll |
| 04/2022 - 03/2025 | Freie Dozentin (Humanmedizin), Medical School Hamburg (MSH) |
| 10/2022 - 09/2023 | Praktische Tätigkeit im Rahmen der Psychotherapieausbildung, Klinik für Gerontopsychiatrie, Asklepios Klinik Nord-Ochsenzoll |
| 01/2019 - 12/2021 | Wissenschaftliche Mitarbeiterin, Institut für Translationale Psychiatrie, Universitätsklinikum Münster |
| 12/2016 - 03/2018 | Wissenschaftliche Hilfskraft, Institut für Psychologie I, Universität zu Lübeck |
| 01/2015 - 09/2016 | Wissenschaftliche Hilfskraft, Institut für Medizinische Psychologie und Systemneurowissenschaften sowie Klinik für Psychiatrie, Universitätsklinikum Münster |
Ausbildung
| Seit 04/2022 | Weiterbildung zur psychologischen Psychotherapeutin (VT), Institut für Verhaltenstherapie-Ausbildung Hamburg (IVAH gGmbH) |
| 01/2020 - 12/2022 | Promotionsstudium, Dissertation: „The Neurobiology of Disease Course in Major Depressive Disorder“, Institut für Translationale Psychiatrie, Universitätsklinikum Münster (Betreuer: Prof. Dr. Dr. Udo Dannlowski) |
| 10/2016 - 12/2018 | Master of Science in Psychologie, Schwerpunkt: Klinische Psychologie und Neurowissenschaft, Universität zu Lübeck |
| 10/2013 - 09/2016 | Bachelor of Science in Psychologie, Universität Münster |
Lehre
| 2025 | Seminar “Kasuistiken im Kindes- und Jugendalter” (B.Sc. Psychologie), Universität Hamburg |
| 2022 - 2025 | Seminar “Medizinische Psychologie” (Humanmedizin), Medical School Hamburg (MSH) |
| 2022 | Seminar “Medizinische Psychologie” (B.A. Medizinpädagogik) Medical School Hamburg (MSH) |
| 2021 | Gastvortrag im Seminar “MRT-Forschung in der Psychiatrie: von den Grundlagen zur Auswertung” über “Resting State Functional Connectivity”, Institut für Translationale Psychiatrie, Universitätsklinikum Münster |
Workshops
| 2021 | Virtueller Workshop des ECNP for Early Career Scientists in Europe |
| 2020 | Seminar: “Maschinelles Lernen für Mediziner”, Prof. Dr. Tim Hahn, Universität Münster |
| 2019 |
Scientific Writing Workshop, Dr. Celeste Brennecka, Universität Münster SPM-Workshop, Dr. Tobias Sommer & Dr. Jan Gläscher, Universität Hamburg CAT12-Workshop, Dr. Christian Gaser, Universität Hamburg |
Konferenzbeiträge
| 2021 |
Vortrag beim Workshop für Early Career Scientists in Europa (virtuell): „Associations between abnormal brain function during emotion processing and lifetime disease course in major depressive disorder“ Poster beim ECNP-Kongress, Lissabon, Portugal: “Associations between abnormal brain function during emotion processing and lifetime disease course in major depressive disorder“ Vortrag beim DGPPN-Kongress, Berlin, Deutschland: „Verringertes Hippocampus-Volumen bei Patient:innen mit Major Depression – Zusammenhang zum Remissionsgrad“ |
| 2020 | Poster beim ECNP-Kongress (virtuell): “Replication of effects of cumulative illness severity on hippocampal gray matter volume in the FOR2107 cohort” |
| 2019 | Poster beim DGPPN-Kongress, Berlin, Deutschland: “Replication of effects of cumulative illness severity on hippocampal gray matter volume in the FOR2107 cohort” |
Auszeichnungen
| 2021 |
Stipendium für den ECNP Workshop for Early Career Scientists in Europe, Nizza, Frankreich (abgesagt aufgrund der COVID-19-Pandemie) Exzellenzpreis und Reisestipendium für den ECNP-Kongress in Lissabon, Portugal (500 €) |
Publikationsliste
2024
1. Klug, M., Enneking, V., Borgers, T., Jacobs, C. M., Dohm, K., Kraus, A., . . . Lemke, H., . . . Redlich, R. (2024). Persistence of amygdala hyperactivity to subliminal negative emotion processing in the long-term course of depression. Molecular Psychiatry, 29(5), 1501–1509. https://doi.org/10.1038/s41380-024-02429-4
2. Thiel, K.*, Lemke, H.*, Winter, A., Flinkenflügel, K., Waltemate, L., Bonnekoh, L., . . . Dannlowski, U. (2024). White and gray matter alterations in bipolar I and bipolar II disorder subtypes compared with healthy controls - exploring associations with disease course and polygenic risk. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology, 49(5), 814–823. https://doi.org/10.1038/s41386-024-01812-7
*both authors contributed equally
3. Sindermann, L., Dannlowski, U., Leehr, E. J., Hahn, T., Grotegerd, D., Meinert, S., . . . Lemke, H., . . . Forstner, A. J. (2024). Neurobiological correlates of comorbidity in disorders across the affective disorders-psychosis spectrum. Journal of Psychiatric Research, 180, 462–472. https://doi.org/10.1016/j.jpsychires.2024.09.052
2023
4. Förster, K., Grotegerd, D., Dohm, K., Lemke, H., Enneking, V., Meinert, S., . . . Lemke, H., . . . Dannlowski, U. (2023). Association of hospitalization with structural brain alterations in patients with affective disorders over nine years. Translational Psychiatry, 13(1), 170. https://doi.org/10.1038/s41398-023-02452-z
5. Goltermann, J., Meinert, S., Hülsmann, C., Dohm, K., Grotegerd, D., Redlich, R., . . . Lemke, H., . . . Dannlowski, U. (2023). Temporal stability and state-dependence of retrospective self-reports of childhood maltreatment in healthy and depressed adults. Psychological Assessment, 35(1), 12–22. https://doi.org/10.1037/pas0001175
6. Goltermann, J., Winter, N. R., Meinert, S., Sindermann, L., Lemke, H., Leehr, E. J., . . . Hahn, T. (2023). Resting-state functional connectivity patterns associated with childhood maltreatment in a large bicentric cohort of adults with and without major depression. Psychological Medicine, 53(10), 4720–4731. https://doi.org/10.1017/S0033291722001623
7. Thiel, K., Meinert, S., Winter, A., Lemke, H., Waltemate, L., Breuer, F., . . . Dannlowski, U. (2023). Reduced fractional anisotropy in bipolar disorder v. Major depressive disorder independent of current symptoms. Psychological Medicine, 53(10), 4592–4602. https://doi.org/10.1017/S0033291722001490
8. Winter, A., Thiel, K., Meinert, S., Lemke, H., Waltemate, L., Breuer, F., . . . Dannlowski, U. (2023). Familial risk for major depression: Differential white matter alterations in healthy and depressed participants. Psychological Medicine, 53(11), 4933–4942. https://doi.org/10.1017/S003329172200188X
2022
9. Enneking, V., Klug, M., Borgers, T., Dohm, K., Grotegerd, D., Frankenberger, L. M., . . . Lemke, H., . . . Redlich, R. (2022). Changes in brain function during negative emotion processing in the long-term course of depression. The British Journal of Psychiatry : The Journal of Mental Science, 221(2), 476–484. https://doi.org/10.1192/bjp.2021.223
10. Lemke, H., Klute, H., Skupski, J., Thiel, K., Waltemate, L., Winter, A., . . . Dannlowski, U. (2022). Brain structural correlates of recurrence following the first episode in patients with major depressive disorder. Translational Psychiatry, 12(1), 349. https://doi.org/10.1038/s41398-022-02113-7
11. Lemke, H., Probst, S., Warneke, A., Waltemate, L., Winter, A., Thiel, K., . . . Dannlowski, U. (2022). The Course of Disease in Major Depressive Disorder Is Associated With Altered Activity of the Limbic System During Negative Emotion Processing. Biological Psychiatry. Cognitive Neuroscience and Neuroimaging, 7(3), 323–332. https://doi.org/10.1016/j.bpsc.2021.05.008
12. Lemke, H., Romankiewicz, L., Förster, K., Meinert, S., Waltemate, L., Fingas, S., . . . Dannlowski, U. (2022). Association of disease course and brain structural alterations in major depressive disorder. Depression and Anxiety, 39(5), 441–451. https://doi.org/10.1002/da.23260
13. Meinert, S., Leehr, E. J., Grotegerd, D., Repple, J., Förster, K., Winter, N. R., . . . Lemke, H., . . . Dannlowski, U. (2022). White matter fiber microstructure is associated with prior hospitalizations rather than acute symptomatology in major depressive disorder. Psychological Medicine, 52(6), 1166–1174. https://doi.org/10.1017/S0033291720002950
14. Meinert, S., Nowack, N., Grotegerd, D., Repple, J., Winter, N. R., Abheiden, I., . . . Lemke, H., . . . Dannlowski, U. (2022). Association of brain white matter microstructure with cognitive performance in major depressive disorder and healthy controls: A diffusion-tensor imaging study. Molecular Psychiatry, 27(2), 1103–1110. https://doi.org/10.1038/s41380-021-01330-8
15. Sindermann, L., Leehr, E. J., Redlich, R., Meinert, S., Böhnlein, J., Grotegerd, D., . . . Lemke, H., . . . Dannlowski, U. (2022). Emotion processing in depression with and without comorbid anxiety disorder. Journal of Affective Disorders, 314, 133–142. https://doi.org/10.1016/j.jad.2022.06.089
2021
16. Böhnlein, J., Leehr, E. J., Roesmann, K., Sappelt, T., Platte, O., Grotegerd, D., . . . Lemke, H., . . . Dannlowski, U. (2021). Neural processing of emotional facial stimuli in specific phobia: An fMRI study. Depression and Anxiety, 38(8), 846–859. https://doi.org/10.1002/da.23191
17. Förster, K., Danzer, L., Redlich, R., Opel, N., Grotegerd, D., Leehr, E. J., . . . Lemke, H., . . . Dannlowski, U. (2021). Social support and hippocampal volume are negatively associated in adults with previous experience of childhood maltreatment. Journal of Psychiatry & Neuroscience : JPN, 46(3), E328-E336. https://doi.org/10.1503/jpn.200162
2020
18. Enneking, V., Dzvonyar, F., Dück, K., Dohm, K., Grotegerd, D., Förster, K., . . . Lemke, H., . . . Redlich, R. (2020). Brain functional effects of electroconvulsive therapy during emotional processing in major depressive disorder. Brain Stimulation, 13(4), 1051–1058. https://doi.org/10.1016/j.brs.2020.03.018
19. Repple, J., Mauritz, M., Meinert, S., Lange, S. C. de, Grotegerd, D., Opel, N., . . . Lemke, H., . . . van den Heuvel, M. P. (2020). Severity of current depression and remission status are associated with structural connectome alterations in major depressive disorder. Molecular Psychiatry, 25(7), 1550–1558. https://doi.org/10.1038/s41380-019-0603-1
2018
20. Voegler, R., Peterburs, J., Lemke, H., Ocklenburg, S., Liepelt, R., & Straube, T. (2018). Electrophysiological correlates of performance monitoring under social observation in patients with social anxiety disorder and healthy controls. Biological Psychology, 132, 71–80. https://doi.org/10.1016/j.biopsycho.2017.11.003
Publikationen im Rahmen von Konsortien und Forschungsgruppen (e.g. DFG Forschergruppe FOR2107, ENIGMA)
21. Brosch, K., Meller, T., Pfarr, J.‑K., Stein, F., Schmitt, S., Ringwald, K., . . . Lemke, H., . . . Kircher, T. (2022). Which traits predict elevated distress during the Covid-19 pandemic? Results from a large, longitudinal cohort study with psychiatric patients and healthy controls. Journal of Affective Disorders, 297, 18–25. https://doi.org/10.1016/j.jad.2021.10.017
22. Brosch, K., Stein, F., Meller, T., Schmitt, S., Yuksel, D., Ringwald, K., . . . Lemke, H., . . . Krug, A. (2021). Dlpfc volume is a neural correlate of resilience in healthy high-risk individuals with both childhood maltreatment and familial risk for depression. Psychological Medicine, 52(16), 1–7. https://doi.org/10.1017/S0033291721001094
23. Brosch, K., Stein, F., Schmitt, S., Pfarr, J.‑K., Ringwald, K., Thomas-Odenthal, F., . . . Lemke, H., . . . Kircher, T. (2022). Reduced hippocampal gray matter volume is a common feature of patients with major depression, bipolar disorder, and schizophrenia spectrum disorders. Molecular Psychiatry, 27(10), 4234–4243. https://doi.org/10.1038/s41380-022-01687-4
24. Campos, A. I., Thompson, P. M., Veltman, D. J., Pozzi, E., van Veltzen, L. S., Jahanshad, N., . . . Lemke, H., . . . Rentería, M. E. (2021). Brain Correlates of Suicide Attempt in 18,925 Participants Across 18 International Cohorts. Biological Psychiatry, 90(4), 243–252. https://doi.org/10.1016/j.biopsych.2021.03.015
25. Goltermann, J., Repple, J., Redlich, R., Dohm, K., Flint, C., Grotegerd, D., . . . Lemke, H., . . . Opel, N. (2021). Apolipoprotein E homozygous ε4 allele status: Effects on cortical structure and white matter integrity in a young to mid-age sample. European Neuropsychopharmacology : The Journal of the European College of Neuropsychopharmacology, 46, 93–104. https://doi.org/10.1016/j.euroneuro.2021.02.006
26. Groenewold, N. A., Bas-Hoogendam, J. M., Amod, A. R., Laansma, M. A., van Velzen, L. S., Aghajani, M., . . . Lemke, H., . . . van der Wee, N. J. A. (2023). Volume of subcortical brain regions in social anxiety disorder: Mega-analytic results from 37 samples in the ENIGMA-Anxiety Working Group. Molecular Psychiatry, 28(3), 1079–1089. https://doi.org/10.1038/s41380-022-01933-9
27. Gruber, M., Mauritz, M., Meinert, S., Grotegerd, D., Lange, S. C. de, Grumbach, P., . . . Lemke, H., . . . Repple, J. (2023). Cognitive performance and brain structural connectome alterations in major depressive disorder. Psychological Medicine, 53(14), 6611–6622. https://doi.org/10.1017/S0033291722004007
28. Kroemer, N. B., Opel, N., Teckentrup, V., Li, M., Grotegerd, D., Meinert, S., . . . Lemke, H., . . . Walter, M. (2022). Functional Connectivity of the Nucleus Accumbens and Changes in Appetite in Patients With Depression. JAMA Psychiatry, 79(10), 993–1003. https://doi.org/10.1001/jamapsychiatry.2022.2464
29. Krug, A., Stein, F., David, F. S., Schmitt, S., Brosch, K., Pfarr, J.‑K., . . . Lemke, H., . . . Forstner, A. J. (2024). Factor analysis of lifetime psychopathology and its brain morphometric and genetic correlates in a transdiagnostic sample. Translational Psychiatry, 14(1), 235. https://doi.org/10.1038/s41398-024-02936-6
30. Leerssen, J., Blanken, T. F., Pozzi, E., Jahanshad, N., Aftanas, L., Andreassen, O. A., . . . Lemke, H., . . . van Someren, E. J. W. (2020). Brain structural correlates of insomnia severity in 1053 individuals with major depressive disorder: Results from the ENIGMA MDD Working Group. Translational Psychiatry, 10(1), 425. https://doi.org/10.1038/s41398-020-01109-5
31. McWhinney, S. R., Abé, C., Alda, M., Benedetti, F., Bøen, E., Del Mar Bonnin, C., . . . Lemke, H., . . . Hajek, T. (2022). Diagnosis of bipolar disorders and body mass index predict clustering based on similarities in cortical thickness-ENIGMA study in 2436 individuals. Bipolar Disorders, 24(5), 509–520. https://doi.org/10.1111/bdi.13172
32. McWhinney, S. R., Abé, C., Alda, M., Benedetti, F., Bøen, E., Del Mar Bonnin, C., . . . Lemke, H., . . . Hajek, T. (2023). Mega-analysis of association between obesity and cortical morphology in bipolar disorders: Enigma study in 2832 participants. Psychological Medicine, 53(14), 6743–6753. https://doi.org/10.1017/S0033291723000223
33. McWhinney, S. R., Abé, C., Alda, M., Benedetti, F., Bøen, E., Del Mar Bonnin, C., . . . Lemke, H., . . . Hajek, T. (2021). Association between body mass index and subcortical brain volumes in bipolar disorders-ENIGMA study in 2735 individuals. Molecular Psychiatry, 26(11), 6806–6819. https://doi.org/10.1038/s41380-021-01098-x
34. Nenadić, I., Meller, T., Schmitt, S., Stein, F., Brosch, K., Mosebach, J., . . . Lemke, H., . . . Kircher, T. (2022). Polygenic risk for schizophrenia and schizotypal traits in non-clinical subjects. Psychological Medicine, 52(6), 1069–1079. https://doi.org/10.1017/S0033291720002822
35. Nenadić, I., Mosebach, J., Schmitt, S., Meller, T., Stein, F., Brosch, K., . . . Lemke, H., . . . Kircher, T. (2025). Fronto-Thalamic Structural Connectivity Associated With Schizotypy, a Psychosis Risk Phenotype, in Nonclinical Subjects. Schizophrenia Bulletin, 51(Suppl 2), S137-S148. https://doi.org/10.1093/schbul/sbad143
36. Pelin, H., Ising, M., Stein, F., Meinert, S., Meller, T., Brosch, K., . . . Lemke, H., . . . Andlauer, T. F. M. (2021). Identification of transdiagnostic psychiatric disorder subtypes using unsupervised learning. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology, 46(11), 1895–1905. https://doi.org/10.1038/s41386-021-01051-0
37. Pfarr, J.‑K., Brosch, K., Meller, T., Ringwald, K., Schmitt, S., Stein, F., . . . Lemke, H., . . . Nenadić, I. (2021). Brain structural connectivity, anhedonia, and phenotypes of major depressive disorder: A structural equation model approach. Human Brain Mapping, 42(15), 5063–5074. https://doi.org/10.1002/hbm.25600
38. Repple, J., Gruber, M., Mauritz, M., Lange, S. C. de, Winter, N. R., Opel, N., . . . Lemke, H., . . . Dannlowski, U. (2023). Shared and Specific Patterns of Structural Brain Connectivity Across Affective and Psychotic Disorders. Biological Psychiatry, 93(2), 178–186. https://doi.org/10.1016/j.biopsych.2022.05.031
39. Repple, J., König, A., Lange, S. C. de, Opel, N., Redlich, R., Meinert, S., . . . Lemke, H., . . . Dannlowski, U. (2022). Association Between Genetic Risk for Type 2 Diabetes and Structural Brain Connectivity in Major Depressive Disorder. Biological Psychiatry. Cognitive Neuroscience and Neuroimaging, 7(3), 333–340. https://doi.org/10.1016/j.bpsc.2021.02.010
40. Ringwald, K., Meller, T., Schmitt, S., Andlauer, T. F. M., Stein, F., Brosch, K., . . . Lemke, H., . . . Kircher, T. (2021). Interaction of developmental factors and ordinary stressful life events on brain structure in adults. NeuroImage. Clinical, 30, 102683. https://doi.org/10.1016/j.nicl.2021.102683
41. Ringwald, K., Pfarr, J.‑K., Schmitt, S., Stein, F., Brosch, K., Meller, T., . . . Lemke, H., . . . Kircher, T. (2022). Interaction of recent stressful life events and childhood abuse on orbitofrontal grey matter volume in adults with depression. Journal of Affective Disorders, 312, 122–127. https://doi.org/10.1016/j.jad.2022.06.050
42. Ringwald, K., Pfarr, J.‑K., Stein, F., Brosch, K., Meller, T., Thomas-Odenthal, F., . . . Lemke, H., . . . Kircher, T. (2022). Association between stressful life events and grey matter volume in the medial prefrontal cortex: A 2-year longitudinal study. Human Brain Mapping, 43(11), 3577–3584. https://doi.org/10.1002/hbm.25869
43. Schmitt, S., Ringwald, K., Meller, T., Stein, F., Brosch, K., Pfarr, J.‑K., . . . Lemke, H., . . . Kircher, T. (2023). Associations of gestational age with gyrification and neurocognition in healthy adults. European Archives of Psychiatry and Clinical Neuroscience, 273(2), 467–479. https://doi.org/10.1007/s00406-022-01454-0
44. Stein, F., Buckenmayer, E., Brosch, K., Meller, T., Schmitt, S., Ringwald, K., . . . Lemke, H., . . . Kircher, T. (2022). Dimensions of Formal Thought Disorder and Their Relation to Gray- and White Matter Brain Structure in Affective and Psychotic Disorders. Schizophrenia Bulletin, 48(4), 902–911. https://doi.org/10.1093/schbul/sbac002
45. Stein, F., Meller, T., Brosch, K., Schmitt, S., Ringwald, K., Pfarr, J. K., . . . Lemke, H., . . . Kircher, T. (2021). Psychopathological Syndromes Across Affective and Psychotic Disorders Correlate With Gray Matter Volumes. Schizophrenia Bulletin, 47(6), 1740–1750. https://doi.org/10.1093/schbul/sbab037
46. Stein, F., Schmitt, S., Brosch, K., Meller, T., Pfarr, J.‑K., Ringwald, K., . . . Lemke, H., . . . Krug, A. (2023). State of illness-dependent associations of neuro-cognition and psychopathological syndromes in a large transdiagnostic cohort. Journal of Affective Disorders, 324, 589–599. https://doi.org/10.1016/j.jad.2022.12.129
47. Struck, N., Krug, A., Feldmann, M., Yuksel, D., Stein, F., Schmitt, S., . . . Lemke, H., . . . Brakemeier, E.‑L. (2020). Attachment and social support mediate the association between childhood maltreatment and depressive symptoms. Journal of Affective Disorders, 273, 310–317. https://doi.org/10.1016/j.jad.2020.04.041